alpha B Crystallin Polyclonal Antibody, Invitrogen™

alpha B Crystallin Antibody, PA1-16950, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-16950

ALPHA B CRYSTALLIN

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11561812

Quantity Price
1 £ 257.0 / 100µL
Estimated Shipment date
from Supplier 16-02-2017
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Description and Specification

Specification

Formulation 100μL purified antibody (1.08mg/mL) in tris citrate and 0.1% sodium azide; pH 7-8
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Western Blot
Cross Reactivity Human
Cross Reactivity Mouse
Antigen alpha B Crystallin
Storage Requirements Store at 4° C
Immunogen Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.
Isotype IgG
Primary or Secondary Primary
Format Purified
Gene Accession No. P02511, P23927
Host Species Rabbit
Conjugate Unlabeled
Species Reactivity Human, Mouse
Gene Alias Alpha crystallin B chain antibody, CryAB antibody, Alpha (B)-crystallin antibody, Rosenthal fiber componet antibody, Heat-shock protein beta-5 antibod
Gene Symbols CRYAB
Quantity 100μL
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 12955, 1410

Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.
Formulation: 100μL purified antibody (1.08mg/mL) in tris citrate and 0.1% sodium azide; pH 7-8
Synonyms: Alpha crystallin B chain antibody, CryAB antibody, Alpha (B)-crystallin antibody, Rosenthal fiber componet antibody, Heat-shock protein beta-5 antibod
Uniprot Accession: P02511, P23927
Entrez GeneID: 12955, 1410
Gene Symbol: CRYAB
This Crystallin AB antibody is useful for Western blot analysis, where a band is seen at ∽20 kDa. There is also a band of greater intensity at ∽40 kDa that may be an aggregated heteromeric complex. CryAB aggregates with homologous proteins, including CryAA and the small heat shock protein HSP28, to form large heteromeric complexes.Suggested positive control: human and mouse skeletal muscle lysate, human skeletal muscle protein, antigen standard for HSPB1 (transient overexpression lysate), mouse skeletal muscle protein.