ANT1/2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16895424	Proteintech 15997-1-AP-20UL	20 μL
16885424	Proteintech 15997-1-AP-150UL	150 μL

Description

This antibody recognizes both of ANT1 and ANT2.

Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintece of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.

Specifications

• Antigen: ANT1/2
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Human, Mouse
• Gene Accession No.: P05141, P12235, P48962, P51881, Q05962, Q09073
• Gene ID (Entrez): 11739, 11740, 25176, 291, 292, 85333
• Immunogen: ANT1/2 Fusion Protein Ag7787
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SLC25A4

• Concentration: 0.33 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: AAC1, ADP,ATP carrier protein 1, ADP/ATP translocase 1, ANT, ANT 1, ANT1/2, PEO2, PEO3, SLC25A4, T1
• Gene Symbols: SLC25A4, Slc25a5
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody