Andropanolide, MedChemExpress

Product Code. 16431658

Brand: Medchem Express HYN1912

Description

MedChemExpress Andrographolide (Andro) is a small antagonist for NF-κB activation by covalent modifying reduced cysteine 62 of p50.

Andrographolide is a bicyclic diterpenoid lactone mainly produced from the plant Andrographis (Andrographis paniculate). Andrographolide suppresses the activation of NF-κB in stimulated endothelial cells, which reduces the expression of cell adhesion molecule E-selectin and prevents E-selectin-mediated leukocyte adhesion, but has no effect on IκBα degradation, p50 and p65 nuclear translocation.

Specifications

• Chemical Name or Material: Andropanolide
• CAS: 869807-57-8
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₂₀H₃₀O₅
• Quantity: 5 mg
• SMILES: O=C1OC[C@@H](O)/C1=C/C[C@@H]2C(CC[C@]3([H])[C@](C)(CO)[C@H](O)CC[C@@]23C)=C
• Molecular Weight (g/mol): 350.45
• Formula Weight: 350.45
• Percent Purity: 98.78%
• Grade: Research
• Physical Form: Powder
• For Use With (Application): COVID-19-immunoregulation

Research purposes only