AMZ2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA550330

Product Code. 15614265

Description

The antibody detects endogenous levels of total AMZ2 protein.

AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.

Specifications

• Antigen: AMZ2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AMZ2
• Gene Alias: AA408420; Amz2; archaelysin family metallopeptidase 2; archaemetzincin-2; archaemetzincins-2; archeobacterial metalloproteinase-like 2; archeobacterial metalloproteinase-like protein 2; BM-014; ESTM12; RGD1304846; X83328
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51321
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q86W34
• Gene Symbols: AMZ2
• Immunogen: Fusion protein corresponding to residues near the C terminal of human archaelysin family metallopeptidase 2
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG