Invitrogen™ Amylin Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102889

Product Code. 16639344

Description

Antibody detects endogenous levels of total Amylin.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Specifications

• Antigen: Amylin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IAPP
• Gene Alias: Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15874, 24476, 3375
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P10997, P12968, P12969
• Gene Symbols: IAPP
• Immunogen: A synthesized peptide derived from human IAPP(Accession P10997), corresponding to amino acid residues F9-I59.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG