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Amuvatinib, MedChemExpress

Product Code. 16490087
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Product Code. 16490087 Supplier Medchem Express Supplier No. HY10206

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MedChemExpress Amuvatinib (MP470) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. Amuvatinib (MP470) is also a DNA repair suppressor through suppression of DNA repair protein RAD51, thereby disrupting DNA damage repair. Antineoplastic activity.

Amuvatinib (MP470) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. Amuvatinib (MP470) is also a DNA repair suppressor through suppression of DNA repair protein RAD51, thereby disrupting DNA damage repair. Antineoplastic activity.

Specifications

Chemical Name or Material Amuvatinib
CAS 850879-09-3
Color Off-White
Purity Grade Notes Research
Molecular Formula C23H21N5O3S
Quantity 50 mg
Synonym MP470 HPK 56
Solubility Information DMSO : 50 mg/mL (111.73 mM; Need ultrasonic)
SMILES S=C(N1CCN(C2=C3OC4=CC=CC=C4C3=NC=N2)CC1)NCC5=CC=C6OCOC6=C5
Molecular Weight (g/mol) 447.51
Formula Weight 447.51
Percent Purity 98.07%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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