Invitrogen™ AMPK gamma-2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA517561

Product Code. 11522460

Description

It is not recommended to aliquot this antibody.

AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: AMPK gamma-2
• Classification: Polyclonal
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: Q91WG5, Q9UGJ0
• Gene Symbols: PRKAG2
• Immunogen: Synthetic peptide correspoding to residues surrounding Ser60 of human AMPKgamma2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey, Bovine
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: PRKAG2
• Gene Alias: 2410051C13Rik; 5'-AMP-activated protein kinase subunit gamma-2; 5-AMP-activated protein kinase, gamma-2 subunit; AAKG; AAKG2; adenosine monophosphate-activated protein kinase gamma 2-subunit; AI854673; AMP-activated protein kinase gamma2 subunit; ampk gamma; AMPK gamma 2; AMPK gamma2; AMPK gamma-2 chain; AMPK subunit gamma-2; CMH6; H91620p; OTTHUMP00000211956; PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; WPWS
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 108099, 373545, 504219, 51422
• Content And Storage: -20°C
• Form: Liquid