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  6. AMPK alpha 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

AMPK alpha 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16878224 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16878224 20 μL 20µL
16868224 150 μL 150µL
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Product Code. 16878224 Supplier Proteintech Supplier No. 181671AP20UL

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Description

Rabbit Polyclonal Antibody

AMPK2 alpha2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Specifications

Antigen AMPK alpha 2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PRKAA2
Gene Accession No. P54646, Q09137, Q8BRK8
Gene Alias AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, AMPKA2, AMPKalpha2, PRKAA, PRKAA2
Gene Symbols PRKAA2
Host Species Rabbit
Immunogen AMPK alpha 2 Fusion Protein Ag12796
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108079, 5563, 78975
Target Species Human, Rat, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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