Thermo Scientific Chemicals Ampicillin, Ready-to-Use aqueous soln., 100mg/mL, 0.2 micron filtered

Product Code.	Quantity	unitSize
15440677	10 mL	10mL

Product Code. 15440677 Supplier Thermo Scientific Chemicals Supplier No. J66972.AB

Description

Ampicillin, CAS # 69-53-4, is structurally related to penicillin and is considered to be a semi-synthetic antibiotic with antibacterial activity. | CAS: 69-53-4 | C16H19N3O4S | 349.405 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Ampicillin is a broad-spectrum, semi-synthetic, β-lactam penicillin with bactericidal activity. It acts against several gram-positive and -negative infections
• This compound binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. This inactivation interferes with the cross-linkage of peptidoglycan chains essential for bacterial cell wall strength and rigidity. Consequently, there is an interruption in the bacterial cell wall synthesis which results in the weakening of the bacterial cell wall causing cell lysis

Application

• In laboratory experiments, it is commonly used as a selector reagent for transformed cells expressing β-lactamase. The ampicillin-resistant gene (ampR) catalyzes the hydrolysis of the β-lactam ring of ampicillin and naturally detoxifies the drug
• Ampicillin is commonly used as a selection marker for E. coli and other bacteria during plasmid DNA isolation, protein expression, and gene cloning

Specifications

Chemical Identifiers

• CAS: 69-53-4
• Molecular Formula: C16H19N3O4S
• Molecular Weight (g/mol): 349.405
• InChI Key: AVKUERGKIZMTKX-NJBDSQKTSA-N
• PubChem CID: 6249
• ChEBI: CHEBI:28971
• IUPAC Name: (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C

• Type: Ampicillin
• Physical Form: Liquid
• Odor: Odorless
• Color: Yellow
• Quantity: 10 mL
• Sensitivity: Light sensitive
• Chemical Name or Material: Ampicillin, eady-to-Use aqueous soln., 100mg/mL, 0.2 micron filtered

Safety and Handling

Product Identifier

• Ampicillin, Ready-to-Use aqueous solution

Signal Word

• Danger

Hazard Category

• Respiratory sensitiser Category 1
• Skin sensitiser Category 1

Hazard Statement

• H317-May cause an allergic skin reaction.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P284-[In case of inadequate ventilation] wear respiratory protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
• P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .

Supplemental information

• MIXTURE LIST-Contain: Sodium [2S-[2.alpha.,5.alpha.,6.beta.(S*)]]-6-(amino phenylacetamido)-3,3-dimethyl-7-oxo-4-thia -1-a

SDS

RUO – Research Use Only