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AMI-1, MedChemExpress

Product Code. 16477658
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Product Code. 16477658 Supplier Medchem Express Supplier No. HY18962

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Description

MedChemExpress AMI-1 is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 exerts PRMTs inhibitory effects by blocking peptide-substrate binding.

AMI-1 is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 exerts PRMTs inhibitory effects by blocking peptide-substrate binding.

Specifications

Chemical Name or Material AMI-1
CAS 20324-87-2
Color Coffee
Purity Grade Notes Research
Molecular Formula C21H14N2Na2O9S2
Quantity 10 mg
Solubility Information H2O : 62.5 mg/mL (113.96 mM; ultrasonic and warming and heat to 60°C)
SMILES O=C(NC1=CC2=CC(S(=O)(O[Na])=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)(O[Na])=O)=CC(O)=C4C=C3
Molecular Weight (g/mol) 548.45
Formula Weight 548.45
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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