Invitrogen™ AMER2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558794

Product Code. 15796661

Description

Immunogen sequence: VDDTYLQEFW DMLSQTEEQG PEPQEGAAKV AAALETKVVP ETPKDTRCVE AAKDASSVKR RRLNRIPIEP HPKEEPKHPE KEQQE Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.

Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.

Specifications

• Antigen: AMER2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AMER2
• Gene Alias: 2600011E07Rik; AMER2; APC membrane recruitment 2; APC membrane recruitment protein 2; Fam123a; family with sequence similarity 123, member A; family with sequence similarity 123A; protein FAM123A; RGD1559605
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 219287
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N7J2
• Gene Symbols: AMER2
• Immunogen: Recombinant protein corresponding to Human AMER2. Recombinant protein control fragment (Product #RP-97993).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG