AMD 3465 hexahydrobromide, Tocris Bioscience™

Description

Potent and selective CXCR4 antagonist

Potent, selective CXCR4 antagonist; exhibits 8-fold higher affinity than AMD 3100 (Cat.No. 3299). Inhibits SDF-1α-ligand binding (Ki = 41.7 nM). Potently inhibits HIV cell entry in vitro; causes leukocytosis and mobilizes haematopoietic stem cells in vivo.

Specifications

• CAS: 185991-07-5
• Molecular Formula: C24H44Br6N6
• Quantity: 10mg
• Synonym: amd 3465 hexahydrobromide, pyridin-2-ylmethyl 4-1,4,8,11-tetraazacyclotetradecan-1-ylmethyl phenyl methyl amine hexahydrobromide, n-4-1,4,8,11-tetraazacyclotetradec-1-ylmethyl phenyl methyl-2-pyridinemethanamine hexahydrobromide, amd3465 hexahydrobromide, amd3465 6 hbr, n-pyridin-2-ylmethyl-1-4-1,4,8,11-tetrazacyclotetradec-1-ylmethyl phenyl methanamine hexahydrobromide
• InChI Key: ARHBIBDGWDRBJH-UHFFFAOYSA-N
• SMILES: C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3.Br.Br.Br.Br.Br.Br
• IUPAC Name: N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine;hexahydrobromide
• Molecular Weight (g/mol): 896.082
• PubChem CID: 9897616
• Formula Weight: 896.07
• Percent Purity: >97%
• Chemical Name or Material: AMD 3465 hexahydrobromide