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  6. AMD 3465 hexahydrobromide, MedChemExpress

AMD 3465 hexahydrobromide, MedChemExpress

Product Code. 16497016
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Product Code. 16497016

Brand: Medchem Express HY15971

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Description

MedChemExpress AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses.

AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells

Specifications

Chemical Name or Material AMD 3465 hexahydrobromide
Physical Form Solid
CAS 185991-07-5
Color Light Yellow
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C24H44Br6N6
For Use With (Application) COVID-19-anti-virus
Synonym GENZ-644494 hexahydrobromide
Solubility Information DMSO : 50 mg/mL (55.80 mM; Need ultrasonic) ∣H2O : ≥ 38 mg/mL (42.41 mM)
SMILES [H]Br.[H]Br.[H]Br.[H]Br.[H]Br.[H]Br.C1(CNCC2=CC=C(CN3CCNCCCNCCNCCC3)C=C2)=NC=CC=C1
Molecular Weight (g/mol) 896.07
Formula Weight 896.07
Percent Purity 98.0%
Grade Research
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Research purposes only

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