Alvimopan dihydrate, MedChemExpress

Product Code. 16458218

Brand: Medchem Express HY76657A

Description

MedChemExpress Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus.

Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus.

Specifications

• Chemical Name or Material: Alvimopan dihydrate
• CAS: 170098-38-1
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₂₅H₃₆N₂O₆
• Quantity: 10 mg
• Synonym: ADL 8-2698 dihydrate LY 246736 dihydrate
• Solubility Information: DMSO : 33.33 mg/mL (72.37 mM; Need ultrasonic)
• SMILES: OC1=CC=CC([C@@]2(C)[C@@H](C)CN(C[C@H](CC3=CC=CC=C3)C(NCC(O)=O)=O)CC2)=C1.O.O
• Molecular Weight (g/mol): 460.56
• Formula Weight: 460.56
• Percent Purity: 98.7%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Neuroscience-Neuromodulation

Research purposes only