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Aluminon

Product Code. 11458366
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Product Code. 11458366 Supplier Thermo Scientific Alfa Aesar Supplier No. A15401.09
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CAS: 569-58-4 | C22H23N3O9 | 473.438 g/mol

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

Solubility
Soluble in water(800g/L).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 569-58-4
Molecular Formula C22H23N3O9
Molecular Weight (g/mol) 473.438
MDL Number MFCD00040925
InChI Key AIPNSHNRCQOTRI-UHFFFAOYSA-N
Synonym Aurintricarboxylic acid triammonium salt
PubChem CID 54729869
ChEBI CHEBI:87398
IUPAC Name triazanium;5-[(3-carboxy-4-oxidophenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-oxidobenzoate
SMILES C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]

Specifica

Melting Point 220°C to 225°C (decomposition)
Odor Odorless
Merck Index 14,322
Solubility Information Soluble in water(800g/L).
pH 5.3
Quantity 10 g
Formula Weight 473.44
Chemical Name or Material Aluminon
What is the solubility of Aluminon?

Aluminon is soluble in water at a concentration of ~800 g/L at 20°C. It is slightly soluble in ethanol and insoluble in petroleum ether.

compliance-icons
Identificativo prodotto
  • Aluminon
Avvertenza
  • Warning
Categoria di pericolo
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
Indicazioni di pericolo
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
Consigli di prudenza
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Informazioni supplementari
  • MIXTURE LIST-Contain: Aluminon

RUO – Research Use Only

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