Aluminon

Product Code. 11458366

Brand: Thermo Scientific Alfa Aesar A15401.09

Description

CAS: 569-58-4 | C22H23N3O9 | 473.438 g/mol

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

Solubility
Soluble in water(800g/L).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifikationer

Kemiska identifierare

• CAS: 569-58-4
• Molecular Formula: C22H23N3O9
• Molecular Weight (g/mol): 473.438
• MDL Number: MFCD00040925
• InChI Key: AIPNSHNRCQOTRI-UHFFFAOYSA-N
• Synonym: Aurintricarboxylic acid triammonium salt
• PubChem CID: 54729869
• ChEBI: CHEBI:87398
• IUPAC Name: triazanium;5-[(3-carboxy-4-oxidophenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-oxidobenzoate
• SMILES: C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]

• Melting Point: 220°C to 225°C (decomposition)
• Merck Index: 14,322
• Solubility Information: Soluble in water(800g/L).
• Formula Weight: 473.44
• Odor: Odorless
• pH: 5.3
• Quantity: 10 g
• Chemical Name or Material: Aluminon

Frequently Asked Questions (FAQs)

What is the solubility of Aluminon?

Aluminon is soluble in water at a concentration of ~800 g/L at 20°C. It is slightly soluble in ethanol and insoluble in petroleum ether.

Säkerhet och hantering

Produktbeteckning

• Aluminon

Signalord

• Warning

Riskkategorier

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2

Faroangivelser

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.

Skyddsangivelse

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Kompletterande information

• MIXTURE LIST-Contains : Aluminon

SDS

RUO – Research Use Only