Aluminon, ACS

Product Code.	Quantity	unitSize
11343298	100 g	100g
10457090	100 g	500mL
11333298	25 g	25g

Product Code. 11343298 Supplier Thermo Scientific Alfa Aesar Supplier No. 036239.22

Description

CAS: 569-58-4 | C22H23N3O9 | 473.438 g/mol

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca2+ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca2+-activated protease that is activated during apoptosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Spécification

Identifiants chimiques

• CAS: 569-58-4
• Molecular Formula: C22H23N3O9
• Molecular Weight (g/mol): 473.438
• MDL Number: MFCD00040925
• InChI Key: AIPNSHNRCQOTRI-UHFFFAOYSA-N
• Synonym: aluminon, ammonium aurintricarboxylate, aurintricarboxylic acid ammonium salt, aurintricarboxylic acid, acs
• PubChem CID: 54729869
• ChEBI: CHEBI:87398
• IUPAC Name: triazanium;5-[(3-carboxy-4-oxidophenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-oxidobenzoate
• SMILES: C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]

• Melting Point: 220°C to 225°C (decomposition)
• pH: 5.3
• Odor: Odorless
• Quantity: 100 g
• Merck Index: 14,322
• Solubility Information: Soluble in water(800g/L).
• Formula Weight: 473.44
• Grade: ACS
• Physical Form: Powder
• Chemical Name or Material: Aluminon

Sécurité et traitement

Identifiant produit

• Aluminon, ACS

Mention d'avertissement

• Warning

Catégorie de danger

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2

Mention de danger

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.

Conseils de prudence

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Informations supplémentaires

• MIXTURE LIST-Contain: Aluminon

FDS

RUO – Research Use Only