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Invitrogen™ ALS Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA587723
Description
Immunogen sequence: SCLGRIRPHT FTGLSGLRRL FLKDNGLVGI EEQSLWGLAE LLELDLTSNQ LTHLPHRLFQ GLGKLEYLLL SRNRLAELPA DALGPLQRAF WLDVSHNRLE ALPNSLLAPL GRLRYLSLRN NSLRTFTPQP PGLERLWLEG NPWDCGCPLK ALRDFALQNP SAVPRFVQAI CEGDDCQPPA YTYNNITCAS PPEVVGLDLR DLSEAHFAPC; Positive Samples: Mouse lung, Rat liver; Cellular Location: extracellular space.
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
Specifications
| ALS | |
| Polyclonal | |
| Unconjugated | |
| IGFALS | |
| ACLSD; Albs; Als; IGFALS; insulin like growth factor binding protein acid labile subunit; insulin-like growth factor binding protein complex acid labile chain; insulin-like growth factor binding protein complex acid-labile subunit; insulin-like growth factor binding protein, acid labile subunit; insulin-like growth factor-binding protein complex acid labile chain; insulin-like growth factor-binding protein complex acid labile subunit; mKIAA4111 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 16005, 79438 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.89 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P35859, P70389 | |
| IGFALS | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 396-605 of human IGFALS (NP_0049611). | |
| 100 μL | |
| Primary | |
| Mouse, Rat, Rat | |
| Antibody | |
| IgG |
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