alpha GalCer:CD1d complex Mouse anti-Mouse, PE, Clone: L363, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-2019-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15248719

Quantity Price
1 £ 176.7 / 100µg
EU Stock 1
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Description and Specification

Specification

Conjugate PE
Host Species Mouse
Applications Flow Cytometry
Isotype IgG2a
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100μg
Format Conjugated
Primary or Secondary Primary
Gene Alias alpha GalCer-CD1d complex, alphaGalCerCD1d complex, alpha galcer-CD1d complex, alpha-galactosylceramide, alpha galactosylceramide, CD1d
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Antigen alpha GalCer:CD1d complex
Clone L363
Concentration 0.2mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

This L363 monoclonal antibody reacts with α-galactosylceramide bound to the mouse MHC class I-like protein CD1d. This complex is recognized by invariant natural killer T (iNKT) cells, a subset of T lymphocytes that expresses the invariant TCR α chain Vα14Jα18. Activation of iNKT cells leads to production of Th1 and Th2-associated cytokines as well as dendritic cell maturation.

The L363 antibody has been reported to neutralize iNKT cell activation by α-galactosylceramide:CD1d complexes.