Invitrogen™ alpha Galactosidase Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551364

Product Code. 15759320

Description

Immunogen sequence: HISPQAKALL QDKDVIAINQ DPLGKQGYQL RQGDNFEVWE RPLSGLAWAV AMINRQEIGG PRSYTIAVAS LGKGVACNPA CFITQLLPVK RKLGFYEWTS RLRSHINPTG T Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 69%.

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Specifications

• Antigen: alpha Galactosidase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLA
• Gene Alias: Agalsidase; agalsidase alfa; Ags; Alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase; alpha-D-galactoside galactohydrolase 1; alpha-gal A; alpha-galactosidase A; GALA; galactosidase alpha; galactosidase, alpha; GLA; Melibiase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2717
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.20 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P06280
• Gene Symbols: GLA
• Immunogen: Recombinant protein corresponding to Human alpha Galactosidase. Recombinant protein control fragment (Product #RP-91934).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG