Invitrogen™ alpha COP Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5142630

Product Code. 17816232

Description

Additional Information: This antibody is expected to recognize both reported isoforms (NP_001091868.1; NP_004362.2). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.

Specifications

• Antigen: alpha COP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COPA
• Gene Alias: AILJK; alpha coat protein; alpha-coat protein; Alpha-COP; AU040324; coatomer protein complex subunit alpha; coatomer subunit alpha; COPA; HEPCOP; HEP-COP; proxenin; xenin; Xenopsin-related peptide
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 1314
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P53621
• Gene Symbols: COPA
• Immunogen: Peptide with sequence CTRASNLENST.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG