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Invitrogen™ alpha Actinin 2 Polyclonal Antibody
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Product Code. 13421827
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Quantity:
100 μL
Unit Size:
100µL
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13421827 100 μL 100µL
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Product Code. 13421827 Supplier Invitrogen™ Supplier No. PA527863

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, Neuro2A, GL261, C8D30, NIH-3T3, Rat heart. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (94%), Pig (99%), Chicken (98%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it i involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
TRUSTED_SUSTAINABILITY

Specifications

Antigen alpha Actinin 2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Actn2
Gene Accession No. P35609, Q9JI91
Gene Alias 1110008F24Rik; actinin alpha 2; actinin, alpha 2; ACTN2; alpha-actinin skeletal muscle; Alpha-actinin skeletal muscle isoform 2; Alpha-actinin-2; CMD1AA; CMH23; F-actin cross-linking protein
Gene Symbols Actn2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human alpha Actinin 2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100157406, 11472, 291245, 88
Target Species Human, Mouse, Pig, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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