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alpha-1b Adrenergic Receptor Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA532660
Code : PN
Additional Details : Weight : 0.01000kg
Description
Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey, Marmoset (95%); Mouse, Hamster, Elephant (85%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.Specifications
alpha-1b Adrenergic Receptor | |
Polyclonal | |
Unconjugated | |
Adra1b | |
[a]1b; ADA1B; ADRA1; ADRA1B; Adrenergic alpha 1B- receptor; adrenergic receptor, alpha 1b; adrenergic, alpha-1B-, receptor; adrenoceptor alpha 1B; alpha 1B-adrenoceptor; alpha 1B-adrenoreceptor; alpha-1B adrenergic receptor; Alpha-1B adrenoceptor; alpha-1B adrenoreceptor; alpha-1B-adrenergic receptor; alpha1B-adrenergic receptor; ALPHA1BAR | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
147 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Immunohistochemistry (Paraffin) | |
1 mg/mL | |
PBS with 0.1% sodium azide | |
P35368 | |
Adra1b | |
Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human ADRA1B. | |
50 μg | |
Primary | |
Human | |
Antibody | |
IgG |