Invitrogen™ ALOX5 Monoclonal Antibody (D2), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17919162	Invitrogen™ MA550877	200 μL
17960663	Invitrogen™ MA550878	20 μL

Description

This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Specifications

• Antigen: ALOX5
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: 5 - Lipoxygenase; 5-lipoxygenase; 5LO; 5-LO; 5-LOX; 5LPG; 5LX; AI850497; ALOX5; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; F730011J02; leukotriene A4 synthase; LOG5; LOW QUALITY PROTEIN: arachidonate 5-lipoxygenase; lox5; LOX-5; LOX5A; polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3
• Gene Symbols: ALOX5
• Isotype: IgG2b κ
• Purification Method: Protein A/G
• Gene: ALOX5

• Clone: D2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Rat
• Gene Accession No.: P09917, P12527
• Gene ID (Entrez): 240, 25290
• Immunogen: Recombinant Human 5-LO protein, Glu461-Ser671 (Accession #P09917).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.