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Alosetron Hydrochloride, MedChemExpress

Product Code. 16498178
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Product Code. 16498178

Brand: Medchem Express HY70050C

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Description

MedChemExpress Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist.

Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ∼55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects.

Specifications

Chemical Name or Material Alosetron Hydrochloride
CAS 122852-69-1
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C17H19ClN4O
Quantity 10 mg
Synonym GR 68755CGR 68755 HydrochlorideGR 68755X Hydrochloride
Solubility Information H2O : 33.33 mg/mL (100.75 mM; Need ultrasonic)
SMILES O=C(C(C1=C2C=CC=C1)=C(N2C)CC3)N3CC4=C(NC=N4)C.[H]Cl
Molecular Weight (g/mol) 330.81
Formula Weight 330.81
Percent Purity 99.79%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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