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Allitinib tosylate, MedChemExpress

Product Code. 16471847
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Product Code. 16471847 Supplier Medchem Express Supplier No. HY13427

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Description

MedChemExpress Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity

Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity

Specifications

Chemical Name or Material Allitinib tosylate
CAS 1050500-29-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C31H26ClFN4O5S
Quantity 50 mg
Synonym AST-1306 (TsOH)
Solubility Information DMSO : 50 mg/mL (80.50 mM; Need ultrasonic)
SMILES FC1=CC=CC(COC2=C(Cl)C=C(NC3=NC=NC4=C3C=C(NC(C=C)=O)C=C4)C=C2)=C1.O=S(C5=CC=C(C)C=C5)(O)=O
Molecular Weight (g/mol) 621.08
Formula Weight 621.08
Percent Purity 99.46%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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