Alectinib, MedChemExpress

Product Code.	Quantity	unitSize
16481056	200 mg	200mg
16465478	10 mg	10mg
16456066	100 mg	100mg
16431657	50 mg	50mg
16418197	5 mg	5mg

Product Code. 16481056

Brand: Medchem Express HY13011

Description

MedChemExpress Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

Specifications

• Chemical Name or Material: Alectinib
• CAS: 1256580-46-7
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₃₀H₃₄N₄O₂
• Quantity: 200 mg
• Synonym: CH5424802 RO5424802 AF802
• Solubility Information: DMSO : 6.2 mg/mL (12.85 mM; Need warming)
• SMILES: N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1
• Molecular Weight (g/mol): 482.62
• Formula Weight: 482.62
• Percent Purity: 98.2%
• Grade: Research
• Physical Form: Powder
• For Use With (Application): Cancer-Kinase/protease

Research purposes only