Invitrogen™ Aldolase Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5114841

Product Code. 17267603

Description

Antibody detects endogenous levels of total ALDOA.

Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.

Specifications

• Antigen: Aldolase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ALDOA
• Gene Alias: ALDA; Aldo1; Aldo-1; ALDOA; Aldolase 1; aldolase 1, A isoform; aldolase A; aldolase A, fructose-bisphosphate; aldolase, fructose-bisphosphate A; epididymis secretory sperm binding protein Li 87p; fructose-1,6-bisphosphate triosephosphate-lyase; fructose-bisphosphate aldolase A; GSD12; HEL-S-87p; Lung cancer antigen NY-LU-1; muscle-type aldolase; RNALDOG5; unnamed protein product
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11674, 226, 24189
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P04075, P05064, P05065
• Gene Symbols: ALDOA
• Immunogen: A synthesized peptide derived from human ALDOA(Accession P04075), corresponding to amino acid residues M1-S39.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG