Invitrogen™ ALDH4A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596180

Product Code. 16539021

Description

Immunogen sequence: LYVPHSLWPQ IKGRLLEEHS RIKVGDPAED FGTFFSAVID AKSFARIKKW LEHARSSPSL TILAGGKCDD SVGYFVEPCI VESKDPQEPI MKEEIFGPVL SVYVYPDDKY KETLQLVDST TSYGLTGAVF SQDKDVVQEA TKVLRNAAGN FYINDKSTGS IVGQQPFGGA RASGTNDKPG GPHYILRWTS PQVIKETHKP LGDWSYAYMQ; Positive Samples: HepG2, K-562, A-549, BT-474, Mouse skeletal muscle, Mouse intestine, Mouse kidney; Cellular Location: Mitochondrion matrix.

ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.

Specifications

• Antigen: ALDH4A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Aldh4a1
• Gene Alias: A930035F14Rik; Ahd1; Ahd-1; aldehyde dehydrogenase 4 family member A1; aldehyde dehydrogenase 4 family, member A1; aldehyde dehydrogenase 4A1; aldehyde dehydrogenase family 4 member A1; ALDH4; aldh4a1; Aldh5a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; E330022C09; L-glutamate gamma-semialdehyde dehydrogenase; mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase; P5C dehydrogenase; P5cd; P5CDh; P5cdhl; P5cdhs; RP11-128M10.1; similar to aldehyde dehydrogenase 4 family, member A1; Ssdh1; zgc:63592
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 212647, 8659
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 6.73 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P30038, Q8CHT0
• Gene Symbols: Aldh4a1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 354-563 of human ALDH4A1 (NP_0037392).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG