Invitrogen™ ALDH1A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5114837

Product Code. 17227603

Description

Antibody detects endogenous levels of total ALDH1A2.

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: ALDH1A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ALDH1A2
• Gene Alias: AL1A2; alcohol dehydrogenase family 1, subfamily A2; alcohol dehydrogenase family 1, subfamily A7; aldehyde dehydrogenase 1 family member A2; aldehyde dehydrogenase 1 family, member A2; aldehyde dehydrogenase 1A2; aldehyde dehydrogenase family 1 member A2; aldehyde dehydrogenase family 1, subfamily A2; Aldh1a2; Aldh1a7; AV116159; fb50h01; neckless; nls; nof; no-fin; RALDH 2; RALDH(II); Raldh1; RALDH2; Raldh-2; RALDH2-T; retinal dehydrogenase 2; retinal dehydrogenase, type II; retinaldehyde dehydrogenase 2; retinaldehyde dehydrogenase type 2; retinaldehyde-specific dehydrogenase type 2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116676, 19378, 8854
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O94788, Q62148, Q63639
• Gene Symbols: ALDH1A2
• Immunogen: A synthesized peptide derived from human ALDH1A2(Accession O94788), corresponding to amino acid residues M411-S461.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG