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Invitrogen™ AKR1C1/AKR1C2 Recombinant Rabbit Monoclonal Antibody (23GB3175), Invitrogen™
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Product Code. 30088957
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30088957 100 μL 100µL
30089574 20 μL 20µL
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Product Code. 30088957 Supplier Invitrogen™ Supplier No. MA553602

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Description

Rabbit Recombinant Monoclonal Antibody

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. And this gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AKR1C1/AKR1C2
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB3175
Concentration 0.54 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Akr1c2
Gene Accession No. P52895, Q04828
Gene Alias 17-alpha-HSD; 17-alpha-hydroxysteroid dehydrogenase; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; 2-ALPHA-HSD; 3(or 17)-alpha-hydroxysteroid dehydrogenase; 3-alpha-HSD3; 3-alpha-hydroxysteroid dehydrogenase; AKR1C1; Akr1c2; Akr1c21; Akr1c6; AKR1C-pseudo; aldo-keto reductase C; aldo-keto reductase family 1 member C1; Aldo-keto reductase family 1 member C2; aldo-keto reductase family 1 member C21; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C2; aldo-keto reductase family 1, member C21; aldo-keto reductase family 1, member C6; BABP; C9; chlordecone reductase homolog HAKRC; Chlordecone reductase homolog HAKRD; DD; DD/BABP; DD1; DD1/DD2; DD2; DD-2; DDH; DDH1; DDH2; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; Dihydrodiol dehydrogenase 2; dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III; dihydrodiol dehydrogenase isoform DD1; Dihydrodiol dehydrogenase/bile acid-binding protein; H-37; HAKRC; HAKRD; HBAB; hepatic dihydrodiol dehydrogenase; high-affinity hepatic bile acid-binding protein; Hsd17b5; Indanol dehydrogenase; MBAB; MCDR2; pseudo-chlordecone reductase; SRXY8; TDD; testicular 17,20-desmolase deficiency; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type 5 17beta-hydroxysteroid dehydrogenase; type II 3-alpha-hydroxysteroid dehydrogenase; type II dihydrodiol dehydrogenase; Type III 3-alpha-hydroxysteroid dehydrogenase
Gene Symbols AKR1C1, Akr1c2
Host Species Rabbit
Immunogen A synthetic peptide of human AKR1C1/AKR1C2 (50-101AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1645, 1646
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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