Invitrogen™ AKAP10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA536131

Product Code. 15567531

Description

This antibody detects endogenous protein at a molecular weight of 74 kDa. Purity is >95% by SDS-PAGE.

The A-kinase anchor proteins are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.

Specifications

• Antigen: AKAP10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AKAP10
• Gene Alias: 1500031L16Rik; A kinase (PRKA) anchor protein 10; A kinase anchor protein 10; A kinase anchor protein 10, mitochondrial; Akap10; AKAP-10; A-kinase anchor protein 10, mitochondrial; A-kinase anchoring protein 10; B130049N18Rik; D-akap2; D-AKAP-2; Dual specific A kinase anchoring protein 2; dual specificity A kinase-anchoring protein 2; MGC9414; mitochondrial A kinase PPKA anchor protein 10; PRKA10; protein kinase A anchoring protein 10; protein kinase A-anchoring protein 10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11216
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43572
• Gene Symbols: AKAP10
• Immunogen: Synthetic peptide corresponding to amino acids 1-50 of human AKAP 10.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG