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Aiolos Monoclonal Antibody (8B2), eFluor™ 660, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£111.00 - £298.00

Specifications

Antigen Aiolos
Clone 8B2
Applications Flow Cytometry
Classification Monoclonal
Conjugate eFluor 660
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15331930
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Affymetrix eBioscience
50-5789-82
100 μg
£298.00
100µg
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15321930
View Documents Promotion Details
Affymetrix eBioscience
50-5789-80
25 μg This item is currently unavailable or has been discontinued.
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Description

Description

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Specifications

Specifications

Aiolos
Flow Cytometry
eFluor 660
Mouse
Mouse
22780
IgG1 κ
Affinity chromatography
Ikzf3
8B2
Monoclonal
Liquid
RUO
O08900
Ikzf3
Primary
Antibody
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Documents

Documents

Product Certifications

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