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AIF-1/Iba1 Antibody (rAIF1/1909) - Azide and BSA Free, Novus Biologicals™

Product Code. 18377400 Shop All Bio Techne Products
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Quantity:
100 μg
Unit Size:
100µg
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18377400 100 μg 100µg
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Product Code. 18377400 Supplier Novus Biologicals Supplier No. NBP275760

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Description

Mouse Monoclonal Antibody

AIF-1/Iba1 Monoclonal specifically detects AIF-1/Iba1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AIF-1/Iba1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone rAIF1/1909
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin 1-2 ug/ml
Formulation 10 mM PBS with No Preservative
Gene Accession No. P55008
Gene Alias AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
Gene Symbols AIF1
Host Species Mouse
Immunogen Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)
Molecular Weight of Antigen 16.7 kDa
Purification Method Protein A or G purified
Quantity 100 μg
Research Discipline Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) 199.0
Test Specificity AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Target Species Human
Content And Storage Store at 4°C.
Form Purified
Isotype IgG1 κ
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