Invitrogen™ AID Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588506

Product Code. 16546731

Description

Immunogen sequence: NVRWAKGRRE TYLCYVVKRR DSATSFSLDF GYLRNKNGCH VELLFLRYIS DWDLDPGRCY RVTWFTSWSP CYDCARHVAD FLRGNPNLSL RIFTARLYFC EDRKAEPEGL RRLH; Positive Samples: Mouse brain; Cellular Location: Cytoplasm, Nucleus.

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

Specifications

• Antigen: AID
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Aicda
• Gene Alias: activation induced deaminase; activation-induced cytidine deaminase; Aicda; AID; Arp2; CDA2; Cytidine aminohydrolase; epididymis secretory protein Li 284; HEL-S-284; HIGM2; integrated into Burkitt's lymphoma cell line Ramos; single-stranded DNA cytosine deaminase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11628
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.58 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9WVE0
• Gene Symbols: Aicda
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-130 of human AICDA (NP_0657121).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG