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Invitrogen™ AgRP Polyclonal Antibody

Description
Additional Information: This antibody is expected to recognise both reported isoforms (as represented by NP_001129; NP_015531). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
Specifications
Specifications
| Antigen | AgRP |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 |
| Gene | Agrp |
| Gene Accession No. | O00253 |
| Gene Alias | agouti related neuropeptide; agouti related protein; agouti related protein homolog; agouti-related protein; Agrp; AGRT; ART; ASIP2; orexigenic neuropeptide |
| Gene Symbols | Agrp |
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Product Title
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