Aflatoxin B1, crystalline, Thermo Scientific Chemicals

Artikelnummer. 10593011

Marke: Thermo Scientific Acros 227340010

Beschreibung

Aflatoxin B1, crystalline, CAS # 1162-65-8, is a member of a group of mycotoxins presenting potent hepatotoxic and carcinogenic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Aflatoxin B1 (AFB1) is a member of a group of mycotoxins produced by Aspergillus flavus, and Aspergillus parasiticus showing carcinogenic activities
• AFB1 can induce the transversion of G to T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in a mutation and promoting the carcinogenic process

Applications

• Aflatoxin B1 shows teratogenic activity
• It is a CYP1A2, CYP2A6, CYP2D6, and CYP3A substrate and can be used to study the CYP family in in vitro and in vivo studies.
• It can cause immunosuppression in animal models.

Spezifikation

Chemische Identifikatoren

• CAS: 1162-65-8
• Molecular Formula: C17H12O6
• Molecular Weight (g/mol): 312.28
• MDL Number: MFCD00869647
• InChI Key: OQIQSTLJSLGHID-UHFFFAOYNA-N
• Synonym: ccris 12, aflatoxin b, 2,3,6aalpha,9aalpha-tetrahydro-4-methoxycyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, aflatoxin-b1, unii-9n2n2y55mh, afb1, 1h,11h-cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-4-methoxy-, 6ar,9as, cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, 6ar,9as, aflatoxin b1, cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy
• PubChem CID: 186907
• ChEBI: CHEBI:2504
• IUPAC Name: 11-methoxy-6,8,19-trioxapentacyclo[10.7.0.0²,⁹.0³,⁷.0¹³,¹⁷]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione
• SMILES: COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C2C3C=COC3OC2=C1

• Packaging: Glass bottle
• Quantity: 1 mg
• Merck Index: 15, 171
• Formula Weight: 312.27
• Chemical Name or Material: Aflatoxin B1

Sicherheit und Handhabung

Produktidentifikator

• Aflatoxin B1

Signalwort

• Danger

Gefahrenkategorie

• Acute toxicity Category 1
• Acute toxicity Category 2
• Carcinogenicity Category 1A

Gefahrenhinweis

• H300-Fatal if swallowed.
• H310-Fatal in contact with skin.
• H330-Fatal if inhaled.
• H350-May cause cancer.

Sicherheitshinweis

• P201-Obtain special instructions before use.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P310-Immediately call a POISON CENTER/doctor/.
• P361-Take off immediately all contaminated clothing.

Ergänzende Informationen

• MIXTURE LIST-Contains : Aflatoxine AFB1

Sicherheitsdatenblatt (SDS)

RUO – Research Use Only