Invitrogen™ AFF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA554866

Product Code. 15782791

Description

Immunogen sequence: QGTGNSYTDT SGPKETSSAT PGRDSKTIQK GSESGRGRQK SPAQSDSTTQ RRTVGKKQPK KAEKAAAEEP RGGLKIESET PVDLASSMPS SRHKAATKGS RKPNIKKESK SSPRPTAEKK KYKSTSKSSQ KS Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.

Specifications

• Antigen: AFF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AFF4
• Gene Alias: AF4/FMR2 family member 4; AF4/FMR2 family, member 4; AF5Q31; Aff4; Alf4; ALL1 fused gene from 5q31; ALL1-fused gene from chromosome 5q31 protein; CHOPS; HSPC092; Laf4l; LOW QUALITY PROTEIN: AF4/FMR2 family member 4; major CDK9 elongation factor-associated protein; MCEF; Protein AF-5q31; RA_m002_jsmFBA6Br
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27125
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UHB7
• Gene Symbols: AFF4
• Immunogen: Recombinant protein corresponding to Human AFF4. Recombinant protein control fragment (Product #RP-89295).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG