Invitrogen™ ADH5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA543724

Product Code. 15576202

Description

Peptide sequence: KSVESVPKLV SEYMSKKIKV DEFVTHNLSF DEINKAFELM HSGKSIRTVV Sequence homology: Horse: 79%; Human: 100%; Mouse: 93%; Pig: 79%; Rabbit: 83%; Rat: 86%.

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Specifications

• Antigen: ADH5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADH5
• Gene Alias: ADH1C; Adh2; Adh-2; ADH3; ADH-3; ADH5; Adh-5; ADH-B2; ADHX; alcohol dehydrogenase (class III), chi polypeptide; alcohol dehydrogenase 1C (class I), gamma polypeptide; alcohol dehydrogenase 2; Alcohol dehydrogenase 5; alcohol dehydrogenase 5 (class III), chi polypeptide; alcohol dehydrogenase B2; Alcohol dehydrogenase class chi chain; alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; class III alcohol dehydrogenase; class III alcohol dehydrogenase, chi subunit; epididymis secretory sperm binding protein Li 60p; FALDH; FDH; formaldehyde dehydrogenase; glutathione-dependent formaldehyde dehydrogenase; GSH-FDH; GSNOR; HEL-S-60p; S-(hydroxymethyl)glutathione dehydrogenase; S-nitrosoglutathione reductase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 128
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P11766
• Gene Symbols: ADH5
• Immunogen: Synthetic peptide directed towards the middle region of human ADH5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG