Invitrogen™ Adenylate Kinase 4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596048

Product Code. 16528891

Description

Immunogen sequence: MASKLLRAVI LGPPGSGKGT VCQRIAQNFG LQHLSSGHFL RENIKASTEV GEMAKQYIEK SLLVPDHVIT RLMMSELENR RGQHWLLDGF PRTLGQAEAL DKICEVDLVI SLNIPFETLK DRLSRRWIHP PSGRVYNLDF NPPHVHGIDD VTGEPLVQQE DDKPEAVAAR LRQYKDVAKP VIELYKSRGV LHQFSGTETN KIWPYVYTLF SNKITPIQSK EAY; Positive Samples: HepG2, Raji, SW480, Mouse liver, Mouse kidney; Cellular Location: Mitochondrion matrix.

This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.

Specifications

• Antigen: Adenylate Kinase 4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AK4
• Gene Alias: adenylate kinase 3 alpha-like 1; Adenylate kinase 3-like; adenylate kinase 3-like {ECO:0000255; adenylate kinase 3-like 1; adenylate kinase 3-like 2; adenylate kinase 4; adenylate kinase 4, mitochondrial; adenylate kinase 4, mitochondrial {ECO:0000255; Adenylate kinase isoenzyme 4; adenylate kinase isoenzyme 4, mitochondrial; adenylate kinase isoenzyme 4, mitochondrial; adenylate kinase 4, mitochondrial; AK 4; AK 4 {ECO:0000255; AK3; Ak-3; Ak3b; Ak3l1; AK3L2; AK4; Ak-4; ATP-AMP transphosphorylase; D4Ertd274e; GTP:AMP phosphotransferase AK4; GTP:AMP phosphotransferase AK4 {ECO:0000255; GTP:AMP phosphotransferase AK4, mitochondrial; HAMAP-Rule:MF_03170}; mitochondrial adenylate kinase-3; nucleoside-triphosphate-adenylate kinase; RP4-686B20.1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11639, 205, 29223
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P27144, Q9WUR9, Q9WUS0
• Gene Symbols: AK4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human AK4 (NP_0375421).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG