Invitrogen™ Adenosine Deaminase Monoclonal Antibody (6D4)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA533006

Product Code. 16336414

Description

Human ADA shares 82.5% and 82.9% amino acid (aa) sequence identity with mouse and rat ADA, respectively. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human placenta tissue, human A549 whole cell, human MCF-7 whole cell, human U-937 whole cell, human U20S whole cell, human Caco-2 whole cell. IHC: human colon cancer tissue, human colon cancer tissue, human colon cancer tissue, human rectal cancer tissue, human tonsil tissue. Flow: U20S cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.

Specifications

• Antigen: Adenosine Deaminase
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P00813
• Gene Symbols: ADA
• Immunogen: E.coli-derived human ADA recombinant protein (Position: Q135-L363).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 6D4
• Conjugate: Unconjugated
• Gene: ADA
• Gene Alias: ada; ADA1; adenosine aminohydrolase; Adenosine deaminase; RP11-61L14.5; zgc:92028
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100
• Content And Storage: -20°C
• Form: Lyophilized