Invitrogen™ Human ADCK3, GST Tag Recombinant Protein

Product Code. 15980293

Brand: Invitrogen™ A30969

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This ADCK3 recombinant human protein (156-end) was expressed in insect cells. The purified catalytic domain (135-end) of ADCK3 can be used in a number of different applications, but has been specifically validated for use with our LanthaScreen™ Kinase binding assay technology to identify novel kinase inhibitors. ADCK3 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the LanthaScreen™ Eu Kinase Binding assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Catalytic.

ADCK3 serine/threonine kinase is a mitochondrial protein similar to yeast ABC1 that is a member of the ADCK family. CABC1 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found.

Specifications

• Accession Number: Q8NI60
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 25% glycerol, 10mM glutathione, 0.1mM PMSF, 0.25mM DTT, 0.1mM EDTA, 50mM NaCl and no preservative; pH 7.5
• Gene ID (Entrez): 56997
• Molecular Weight (g/mol): 82.3 kDa
• Name: Human ADCK3, GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 4632432J16Rik; aarF domain containing kinase 3; aarF domain-containing protein kinase 3; Adck3; AI462003; ARCA2; atypical kinase ADCK3, mitochondrial; Atypical kinase COQ8A, mitochondrial; Cabc1; Chaperone activity of bc1 complex-like; chaperone activity of bc1 complex-like, mitochondrial; chaperone, ABC1 activity of bc1 complex homolog; chaperone, ABC1 activity of bc1 complex like; Chaperone-ABC1-like; Coenzyme Q protein 8A; coenzyme Q8 homolog; coenzyme Q8A; COQ10D4; COQ8; COQ8A; mKIAA0451; PP265; SCAR9
• Common Name: CABC1
• Gene Symbol: COQ8A
• KinaseFamily: ACK Kinase Family
• Protein Length: 135-end
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: 135-end
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Catalytic
• Form: Liquid