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  6. Invitrogen™ ADAP Recombinant Rabbit Monoclonal Antibody (K01_1R42)

Invitrogen™ ADAP Recombinant Rabbit Monoclonal Antibody (K01_1R42)

Product Code. 30825409
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30825184 50 μL
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Product Code. 30825409 Supplier Invitrogen™ Supplier No. MA563391

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Description

Rabbit Recombinant Monoclonal Antibody

ADAP Recombinant Monoclonal Antibody for Western Blot

The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-kappa-B family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAP
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1R42
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 150mM NaCl, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene FYB1
Gene Accession No. O15117
Gene Alias ADAP; adhesion and degranulation promoting adaptor protein; adhesion and degranulation-promoting adaptor protein; B630013F22Rik; Fyb; Fyb1; FYB-120/130; FYN binding protein; FYN binding protein (FYB-120/130); FYN binding protein FYB-130; FYN-binding protein; FYN-binding protein 1; FYN-T-binding protein; p120/130; p120/p130; PRO0823; RGD1563421; Slap130; SLAP-130; SLP-76-associated phosphoprotein
Gene Symbols FYB1
Host Species Rabbit
Immunogen A synthetic peptide of human FYB.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2533
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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