Invitrogen™ ADAMTS12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584973

Product Code. 16321925

Description

Immunogen sequence: SYIMEKRYGN LSHVKMMASS APLCHLSGTV LQQGTRVGTA ALSACHGLTG FFQLPHGDFF IEPVKKHPLV EGGYHPHIVY RRQKVPETK Highest antigen sequence indentity to the following orthologs: Mouse - 76%, Rat - 75%.

This protein is a disintegrin and metalloproteinase with thrombospondin motifs-12 (ADAMTS12), which is a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.

Specifications

• Antigen: ADAMTS12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADAMTS12
• Gene Alias: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 12; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12; a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 12; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 12; ADAM metallopeptidase with thrombospondin type 1 motif, 12; ADAMs; ADAM-TS 12; ADAMTS12; ADAM-TS12; ADAMTS-12; AI605170; metalloendopeptidases; metalloprotease disintegrin 12; PRO4389; UNQ1918; UNQ1918/PRO4389
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81792
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P58397
• Gene Symbols: ADAMTS12
• Immunogen: Recombinant protein corresponding to Human ADAMTS12. Recombinant protein control fragment (Product #RP-108646).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG