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ACY-1083, MedChemExpress

Product Code. 16445386
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Product Code. 16445386

Brand: Medchem Express HY111791

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Description

MedChemExpress ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor with an IC50 of 3 nM and is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms. ACY-1083 effectively reverses chemotherapy-induced peripheral neuropathy.

ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor with an IC50 of 3 nM and is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms. ACY-1083 effectively reverses chemotherapy-induced peripheral neuropathy.

Specifications

Chemical Name or Material ACY-1083
CAS 1708113-43-2
Color Off-White
Purity Grade Notes Research
Molecular Formula C17H18F2N4O2
Quantity 100 mg
Solubility Information DMSO : 200 mg/mL (574.14 mM; Need ultrasonic)
SMILES FC(CC1)(F)CCC1(NC2=NC=C(C(NO)=O)C=N2)C3=CC=CC=C3
Molecular Weight (g/mol) 348.35
Formula Weight 348.35
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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