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  6. Invitrogen™ ACVR2B Recombinant Rabbit Monoclonal Antibody (K01_2L28)

Invitrogen™ ACVR2B Recombinant Rabbit Monoclonal Antibody (K01_2L28)

Product Code. 30825826
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30825826 50 μL
30828617 100 μL
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Product Code. 30825826 Supplier Invitrogen™ Supplier No. MA565447

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MTAPWVALAL LWGSLCAGSG RGEAETRECI YYNANWELER TNQSGLERCE GEQDKRLHCY ASWRNSSGTI ELVKKGCWLD DFNCYDRQEC VATEENPQVY Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%, Pig - 98%, Cynomolgus monkey - 99%.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2B
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_2L28
Concentration 0.30 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene ACVR2B
Gene Accession No. P27040, P38445, Q13705
Gene Alias activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Gene Symbols ACVR2B
Host Species Rabbit
Immunogen A synthetic peptide of human Activin Receptor Type IIB/ACVR2B (aa 1-100).
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100755103, 11481, 25366, 93
Target Species Human, Mouse, Rat, Hamster
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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