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Invitrogen™ ACVR2B Polyclonal Antibody
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Product Code. 16579671
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Quantity:
100 μL
Unit Size:
100µL
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16579671 100 μL 100µL
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Product Code. 16579671 Supplier Invitrogen™ Supplier No. PA596838

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EGEQDKRLHC YASWRNSSGT IELVKKGCWL DDFNCYDRQE CVATEENPQV YFCCCEGNFC NERFTHLPEA GGPEVTYEPP PTAPTLLTVL AYSLLPIGGL S; Positive Samples: U-87MG, K-562; Cellular Location: Cell membrane, Single-pass type I membrane protein.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2B
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ACVR2B
Gene Accession No. Q13705
Gene Alias activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Gene Symbols ACVR2B
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACVR2B (NP_0010972).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 93
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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