Invitrogen™ ACVR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA513881

Product Code. 10697620

Description

This antibody is predicted to react with bovine based on sequence homology.

Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. ACVR1 signals a specific transcriptional response in concert with activin type II receptors. The ACVR1 gene encodes activin A type I receptor, which signals a particular transcriptional response in concert with activin type II receptors. Mutations in ACVR1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.

Specifications

• Antigen: ACVR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACVR1
• Gene Alias: activin A receptor type 1; activin A receptor type I; activin A receptor, type 1; activin A receptor, type I; activin A receptor, type II-like kinase 2; activin receptor I precursor; activin receptor type I; Activin receptor type-1; activin receptor-like kinase 2; activin type I receptor; ACTRI; ActR-I; ActRIA; Acvr; ACVR1; ACVR1A; ACVRLK2; ALK2; Alk-2; ALK2-B; Alk8; ATVR1; D330013D15Rik; FOP; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor; serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; Tgfb1; Tsk7L; TSK-7L; TSRI; TSR-I; type I TGF B receptor
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 79558, 90
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P80201, Q04771
• Gene Symbols: ACVR1
• Immunogen: KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human Activin Receptor Type IA (ACVR1).
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG