Invitrogen™ ACTR1B Monoclonal Antibody (4E10)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA520934

Product Code. 15538932

Description

Peptide Sequence: SRYLRLLLRK EGVDFHTSAE FEVVRTIKER ACYLSINPQK DEALETEKVQ YTLPDGSTLD VGPARFRAPE LLFQPDLVGD ESEGLHEVVA FAIHK*.

This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.

Specifications

• Antigen: ACTR1B
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P42025
• Gene Symbols: Actr1b
• Immunogen: ACTR1B (NP_005726, 191 a.a. ~ 286 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Immunocytochemistry
• Clone: 4E10
• Conjugate: Unconjugated
• Gene: Actr1b
• Gene Alias: 2310066K23Rik; AA960180; Actin-related protein 1B; Actr1b; AI851923; ARP1; ARP1 actin-related protein 1 homolog B, centractin beta; ARP1 actin-related protein 1 homolog B, centractin beta (yeast); ARP1 actin-related protein 1B, centractin beta; Arp1b; Beta-centractin; centractin beta; CTRN2; PC3; yeast homolog B
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10120
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid