Invitrogen™ ACTR1A Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA518273

Product Code. 11366243

Description

This antibody is predicted to react with canine, mouse and porcine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

Specifications

• Antigen: ACTR1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACTR1A
• Gene Alias: actin related protein 1A; actin-related protein 1 alpha; actin-related protein 1 homolog A; actin-RPV; ACTR1A; actr1a {ECO:0000250; alpha-Arp1; alpha-centractin; ARP1; ARP1 actin related protein 1 homolog A; ARP1 actin-related protein 1 homolog A, centractin alpha; ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); ARP1 actin-related protein 1A, centractin alpha; Arp1 centractin alpha; Arp1 contractin alpha; Arp1A; centractin; Centrosome-associated actin homolog; CTRN1; FLJ52695; FLJ52800; FLJ55002; UniProtKB:P61163}; yeast homolog A
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10121, 294010, 403791, 54130
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P61162, P61163, P61164, P85515
• Gene Symbols: ACTR1A
• Immunogen: Synthetic peptide sequence (YEEDGARSIHRKT) corresponding to the C-terminus amino acids of ACTR1A (aa 363-376).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine
• Product Type: Antibody
• Isotype: IgG